Inter-Institutional Cooperative Laboratories
Laboratory of Applied Bioresources

Theme
Extreme biology, Molecular mimetics, Genomics
Keyword
Extreme tolerance, Genome, Dry preservation technology
Introduction
I spent all of my time until completing my master's degree in my hometown, Iwate, surrounded by rich nature. When I was a graduate student, I studied the regulation mechanism of gene expression using cultured rat cells. I finally left the Tohoku region when I was offered a job at a national research institute of the Ministry of Agriculture, Forestry and Fisheries in Tsukuba. Since 2000, I have been studying the extreme desiccation tolerance mechanism in the sleeping chironomid, an insect with the ability to survive drought. In the progress of this research, I identified important genes and metabolites involved in the desiccation tolerance Occasionally, I also conducted field sampling of insects that live in extreme environments. Currently, in collaboration with many research institutes in Japan and overseas, I am trying to get closer to the secret of the desiccation tolerance by combining cell engineering techniques such as genomics and genome editing technology using the dry-preservable cultured cell line (Pv11 cells) derived from the sleeping chironomid. Meanwhile, I am developing a technology for dry preservation of proteins and cells at room temperature by applying molecular mechanisms underlying the desiccation tolerance.
Biography
2015 – Present | Associate Professor, Laboratory of Applied Bioresources, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo |
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2019 – Present | Senior Principal Scientist, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO) |
2016 – 2019 | Principal Scientist, Institute of Agrobiological Sciences, NARO |
2009 | Ph. D. Tokyo Institute of Technology |
2006 – 2016 | Principal Researcher, National Institute of Agrobiological Sciences (NIAS) |
2001 – 2006 | Researcher, NIAS |
1994 – 2001 | Researcher, National Institute of Sericultural and Entomological Science |
1994 | M. Sc. The United Graduate School of Agricultural Sciences, Iwate University |
1992 | B. Sc. Department of Agricultural Sciences, Iwate University |